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Abstract

Ascorbic acid commonly referred to as vitamin C, a naturally occurring antioxidant, can lessen the negative effects of ionizing radiation. With regard to medical imaging, contrast agents are frequently employed to improve the visibility of particular body structures throughout X-ray examinations. The purpose of the presented work is using cyclic voltammetric analysis to assess the impact of utilizing contrast medium (iodine solution), both without and with ascorbic acid (AA), on patient blood samples exposed to different X-rays. In this study, we investigate whether the addition of ascorbic acid in combination with a contrast agent, can provide any protective effects against X-ray-induced damage to blood samples. The result shown that the ionized radiation of x-ray acts as oxidative effect on the blood components, and contrast medium enhance the oxidation current peak of the blood medium. But, when using AA with the contrast medium the results have been inhibited the oxidative effect and reduce the oxidation peak into minimum values. Using ascorbic acid (AA) solution is very important to inhibit the oxidative effect of contrast agent with ionizing radiation because AA acts as a good anti-oxidative factor in blood composition. So, it is necessary taking AA solution before exposed to the ionizing radiation by x-ray, so it can be recommended to take AA solution with the contrast medium through scanning x-ray examination.

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