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Abstract

This research was carried out in Ramadi, Iraq, at the Ramadi Teaching Hospital and the Department of Biology laboratories at the University of Anbar's College of Education for Pure Sciences. Samples were collected from different age groups. The study was conducted includes the finding of the role of interferon gamma and granular white blood cells in prevention from Entamoeba histolytica parasite, where the quantitative estimate of interferon gamma was measured using the ELISA technique for the purpose of detecting the concentrations of this cytokine in infected people with amoebiasis and comparing with healthy people to prove the important role of this cytokine during infection with this parasite , The results indicated that there was a statistically significant difference, p≤0.05, in the concentration of INF-γ in samples of affected individuals (78.01 (±9.07)) compared with INF-concentration in control samples (59.18 (±3.937)), Also, the numbers of white blood cells and granulocytes in infected people with this parasite were detected and compared with healthy people using the complete blood count device to detect. The findings indicated a statistically significant distinction, p≤0.05, in the count of White Blood Cells (WBCs) in samples of infected individuals (9.136 (±1.249)) compared to the count of WBC in control samples (6.00 (±0.822)) and that there was a significant difference, p≤0.05, in the count of Granulocytes (Gran) in samples of infected individuals (6.885 (±1.575)) compared to the count of Gran in control samples (4.122 (±0.845)). The results obtained demonstrated the role of granular white blood cells and interferon gamma in combating and controlling this parasite.

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