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Abstract

Alkaline phosphatase is an enzyme produced primarily by the liver. Tests for alkaline phosphatase can be part of routine lab work or part of a series of tests called a liver panel, which includes tests for other liver enzymes, such as aspartate aminotransferase, or alanine aminotransferase. This study aims to find out the effect of alkaline phosphatase enzyme on liver diseases and gallstones. Alkaline phosphatase level was measured for fifty patients suffering from gallstone (30 patients), obstructive disease (10 patients) and liver cirrhosis (10 patients). All patients grouped according to the ages (Each five years as a group), all female patients grouped according to number of pregnancy. The data in this study showed that there is a difference between males and females in terms of age in diseases (gallstones, biliary obstruction and liver diseases) depending on the results of measuring Alkaline phosphatase, where it appeared that the highest results of this enzyme for males with gallstones in the age group (36-45 years) with a concentration of (192.75 IU/L), while for females with gallstones is in the age group (46-55 years) with a concentration of (264 IU/L), as for biliary obstruction, it was in the same age group for both gender (46-55) years, with a concentration of (203.5 IU/L and 345 IU/L) for males and females respectively). As for liver diseases, the age group for males was more than 55 years, and females for the age group (45-55) years (170.33 IU/L and 165 IU/L), respectively. The data also showed the female group with more than 7 time of pregnancy with high concentration of ALP.

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