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Abstract

Serum markers in post-discharged SARS-CoV-2 patients and their relationship with disease severity among recovered patients are poorly described and, in many occasions, might be related to residual effects of the disease. To evaluate the C-reactive protein positivity and the lipid profile after 2-7 months of recovery in SARS-CoV-2 patients. The study also pointed out the frequency of clinical manifestations during the illness course. A total of 27 COVID-19 recovered patients (13 males and 14 females) with an age range of 21-40 year (mean 27.2) were participated in this study. Variable frequency of symptoms as high as fatigue (96.3%), neurological symptoms (92.6%) and as low as pneumonia (7.4%) were reported. 37% of the participants were CRP positive at the discharge time with no gender significant variations. A positive correlation between fever and certain lipid parameters was noticed. The lipid profile was almost returned to its baseline except for HDL which was lower than the normal level with significant differences. CRP positivity in about third of the participants is almost an unexplainable phenomenon and could be due to a low-grade residual COVID-19 inflammatory reaction or a coincidence of other non-COVID-19 infection. The HDL below normal levels may refer to a prolonged lipid-metabolism dysfunction in spite of the 2-7 months after patient’s recovery. The frequency of clinical manifestations was significantly higher in females concerning chest pain, depression, hair loss, joint pain, and CRP positivity.

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