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Abstract

To our knowledge, no study has been conducted on hemogram deviations in apparently healthy individuals (AHI) of blood donors, whom might participate as control groups in clinical studies. Therefore, this study will help to establish the major abnormalities of complete blood picture counts in Iraqi people and uncovering the prevalence of subjects with complete normal hemogram. This cross sectional study was conducted with 217 AHS (103 males and 114) females with ages ranged between (18-69) years with a mean ± SD of 32 ± 13 years from March to October 2019. CBC was performed using Coulter (Ruby-Abbott Diagnosis) USA. Blood donor AHI were distributed 103 male and 114 female with an age ranging from 18-69. The abnormalities in the blood hematological test domain among AHS was for mean platelet volume MPV (66.8%); followed by blood red cell distribution width RDW (61.8%), and mean corpuscle volume MCV (45.2%) and the least frequent was for Blood Monocytes count (1.8%). The prevalence rate (PR) of AHS with a completely normal white blood cell count domain it was 57.2%, for platelets domain tests it was 31.3% and for red blood cell count (RBC) domain it was 11.5%. A totally normal hematological domain tests was found only in 8.8% of tested persons. These results indicate the need for depending special CBP test to determine the suitability of AHS and standardize them to reduce the uncertainty in clinical study, and fortify certification of its conclusions. These results also obviously show that CBP test can aid in selection of AHI taking in account that many deviations in this test can exclude the eligibility of AHI to be chosen as controls.

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