Abstract
Oxidative stress is a physiological state in which high numbers of reactive oxygen species (ROS) and free radicals are produced. It has been demonstrated that oxidative stress plays a role in the development of diabetes. We aimed in this study to assists oxidative stress markers in diabetic patients, such as the oxidation-reduction process and OxLDL, as well as the relationship between OxLDL and the traditional risk factors for type 2 diabetes (LDL, FBS). In addition, various trace metals (copper, zinc, and chromium) were evaluated as antioxidants. The study was conducted at the Specialized Center for Endocrinology and Diabetes in Babylon province, Iraq from the period January- March 2021. In this research a 90 participants were selected, 45 were diagnosed diabetes type 2 and 45 were normal individuals were selected from relative and medical staff with age range (30-70 years). A significant increase of the mean OxLDL of patients group were (598.31 ± 103.61) versus (406.35 ± 90.63) of control group with (P-value= 0.00). The mean LDL of patients were (113.48 ± 27.47) versus (93.59 ± 18.20) of control group, statistically this differences was highly significant (P-value= 0.00). There was a positive association of Ox- LDL, LDL and FBS. The finding revealed that there were significant variances in (zinc, copper and chromium) levels between patients compared with control. A decrease in mean level of zinc and chromium was observed in diabetic patients, while the level of copper in diabetic patients increased compared with the healthy control groups (p <0.01).
First Page
66
Last Page
77
Recommended Citation
Abbas, Noor Kareem; Mohsin, Ahmed A.; H., Humiash H.; and Radhi, Muhammed M.
(2022)
"Estimation of oxidative stress, Oxidized LDL and some trace element in type 2 diabetes mellitus,"
Al-Nisour Journal for Medical Sciences: Vol. 4:
Iss.
2, Article 7.
DOI: https://doi.org/10.70492/2664-0554.1077