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Abstract

Bariatric surgery is the most successful therapy for weight loss, Sleeve gastrectomy; part of the stomach is removed, reducing its capacity by about 85%. Reducing stomach size decreases the consumption of food. Obesity is measured based on their BMI, an estimate of body fat based on weight and height is to study the association between sleeve gastroectomy and some immune marker by estimation level of interleukin-8 (IL-8), interleukin-18 (IL-18), and vitamin D3 in sera patient and control groups, to determination the correlation between in markers; Body mass index (BMI) and their parameters. A total of thirty blood samples were obtained from obese patients with pre and post gastrectomy operative compared with healthy during more than 6 months, the samples preoperative were obtained from the Medical City/Baghdad Teaching Hospital and postoperative for more than 6 months after surgery, taken at home to be the result of pre and post of the sleeve gasterectomy, the age of patients range between (20-46) years for obese patients and similar age group (20-46) year in a healthy person. Then the serum samples were tested to screen the interleukin-8, interleukin-18, and vitamin D by the ELISA method.The study reported that increasing levels of BMI pre-operation, IL-8 pre-operation, and IL-18 pre-operation were increased relative to post-operation. The study reported high BMI, IL-8 and IL-18 pre-operative. The mean value was poor in vitamin D3 preoperation relative to post-operation. The relationships between IL-18, and IL-8 is positive while negative correlation with vitamin D3. The highest mean value of BMI, IL-8, and IL-18 was recorded in preoperation, while the lowest mean was at post-operation. BMI showed a high sensitivity when compared with IL-8, IL-18, vitamin D3.

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