Abstract
Chalcones (3a-3d) were synthesized by two routes conventional and microwave assisted synthesis methods. Claisen-Schmidt reaction (route A) entails base catalyzed cross-aldol condensation of appropriate aldehydes. Microwave aided synthesis (Route B) resulted in a significant increase in reaction rate, as well as higher yields. This method provides a simple, clean, quick, efficient, and cost-effective way to synthesize a large number of organic compounds. The compounds have been screened for they possess a broad spectrum of antibacterial activities.
First Page
58
Last Page
67
Recommended Citation
ADAM, R.; Al-Masoudi, W.; and Ibraheim, H.
(2022)
"Conventional and Microwave Irradiation Methods, Synthesis and Antibacterial Evaluation of Thiophene Chalcones Derivatives,"
Al-Nisour Journal for Medical Sciences: Vol. 4:
Iss.
1, Article 5.
DOI: https://doi.org/10.70492/2664-0554.1065