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Abstract

COVID-19 (Coronavirus disease 2019), cause Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) across all age groups, it’s a positive-sense singlestranded RNA virus, and a member of the Betacoronavirus genus taxonomically. COVID-19 can infect the male reproductive system in large part by inflammatory damage caused by a cytokine storm and the impact of the disease may continue for several months. The ACE2 receptors are highly expressed in testes along with other various tissues of the body making it one of the targets for SARS-CoV-2. The aim is to determine the effect of COVID-19 infections on male reproductive hormones in Iraqi male patients. 120 men chosen from Baghdad Teaching Hospital, 9 Nisan Health Center and Kamal AL-Samarrai Hospital, 70 of them recovered from COVID-19 within a period of 6 months after the last negative PCR nasopharyngeal swab and 50 as control group (uninfected COVID-19) from the Medical staff and the relatives, during the period from December/ 2020 to March / 2021. The measurements of three hormones were done for each one: LH (Luteinizing Hormone), FSH (Follicle-Stimulating Hormone) and Prolactin levels for recovered Covid-19 patients. The mean and standard deviation level of studied parameters are differ between cases of current studying; recovered COVID-19 males and control group then compared with normal value of each test. The levels of LH hormone are slightly increase among recovered males compared with control group, statistically non-significant (P-value= 0.09), as well as FSH hormone among cases are statistically non-significant (P-value= 0.6), while levels of Prolactin hormone are increased among cases studied compared with control group, this differences was highly-significant (Pvalue= 0.006).The levels of LH and FSH among recovered COVID-19 patients did not effected after recover, however there are indirect effect on prolactin level from COVID-19 infections.

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