Abstract
A total of (100) patients attending the Center of Tuberculosis and Chest Disease in Baghdad were included in this study. Their ages ranged between (17-68) years. They all complained of a reproductive cough. The study was accomplished during the period extending from November 2019 till May 2020. Twenty-five were found to have M. tuberculosis by using the Ziehl Neelsen stain and culture technique (15 males, 10 females), their ages ranging between 17 and 68 years. Twenty-five age and sex-matched normal healthy-looking individuals were also chosen as control group for comparison. In this work, the concentrations of the cytokines, interleukine-12(IL-12) and tumor necrotic factor alpha (TNF-α) were evaluated in the sera of Tuberculoid patients by using Enzyme Linked Immunosorbent Assay (ELISA). Results of this work revealed that the mean concentrations of (IL-12 and TNF-α) were significantly higher in the sera of patients with M. tuberculosis infection when compared with their concentration in the sera of the control group (P<0.001). No significant differences were found in the mean concentration of serum (IL-12 and TNF-α) between males and females with M. tuberculosis infection (P>0.05).
First Page
47
Last Page
54
Recommended Citation
Falih, Ekhlas Saddam and obaid, Suhad Hassan
(2020)
"Evaluation of Interleukin- 12 and Tumor necrotic factor- alpha Concentration in Serum of Iraqi Tuberculosis Patients,"
Al-Nisour Journal for Medical Sciences: Vol. 2:
Iss.
1, Article 6.
DOI: https://doi.org/10.70492/2664-0554.1049